Use of Topical Tacrolimus and Topical Pimecrolimus in Four European Countries: A Multicentre Database Cohort Study
نویسندگان
چکیده
منابع مشابه
[Topical pimecrolimus and tacrolimus and the risk of cancer].
In this review the controversy regarding the association between topical pimecrolimus and tacrolimus and the development of tumors is unfolded. After reviewing the literature we conclude that, currently, there is no scientific evidence of an increased incidence of skin cancer, lymphomas or systemic immunosuppression in those patients that use or have used topical calcineurin inhibitors. Publish...
متن کاملLong-term safety of topical pimecrolimus and topical tacrolimus in atopic blepharoconjunctivitis.
Long-term Safety of Topical Pimecrolimus and Topical Tacrolimus in Atopic Blepharoconjunctivitis Atopic blepharoconjunctivitis (ABC) is an ocular manifestation of atopy with a course similar to that of atopic dermatitis: chronic with exacerbations. Topical corticosteroids are widely used for ABC, but longtermuse has awell-established risk of adverse effects: increase of intraocular pressure (IO...
متن کاملFour cases of facial discoid lupus erythematosus successfully treated with topical pimecrolimus or tacrolimus.
Discoid lupus erythematosus (DLE), which is a cutaneous form of lupus erythematosus (LE), is generally refractory to a wide range of topical or systemic therapies. Although the main treatment option for DLE is topical steroids, it is often ineffective or likely to produce long-term side effects. New drugs, including tacrolimus and pimecrolimus, have been developed to overcome the adverse effect...
متن کاملAssociation Between Malignancy and Topical Use of Pimecrolimus.
IMPORTANCE A black box warning describes a potential risk of malignancy associated with topical use of pimecrolimus to treat atopic dermatitis due to its similarity to oral calcineurin inhibitors used in solid-organ transplantation and spontaneous reporting of malignancies, including lymphomas and cutaneous malignancies. OBJECTIVE To evaluate the risk of malignancy in a postmarketing study of...
متن کاملAtopic dermatitis: tacrolimus vs. topical corticosteroid use
Atopic dermatitis (AD), the dermatological manifestation of the atopic diathesis, has a variety of clinical presentations. It is a chronic and relapsing inflammatory disorder, requiring a multifaceted treatment approach. Topical corticosteroids are the backbone of therapy. However, concerns over adverse drug reactions associated with their long-term application limit their use. Tacrolimus, on t...
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ژورنال
عنوان ژورنال: Drugs - Real World Outcomes
سال: 2018
ISSN: 2199-1154,2198-9788
DOI: 10.1007/s40801-018-0133-1